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Blow/Fill/Seal— This type of program brings together the blow-molding of container Together with the filling of item as well as a sealing operation in a single piece of equipment. From the microbiological point of view, the sequence of forming the container, filling with sterile item, and formation and application in the seal are achieved aseptic

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Where by microbial contamination may be a problem, consideration really should be provided to the integrity of your vessel before manufacture.The protocol must contain the objective of The complete method, the scope of your protocol, duties of your departments, the method of cleaning, acceptance conditions and cleaning method validation report.Migh